Post Operative Recurrence and Surgical Outcomes following Crohn’s Ileocolic Resections in Australia

Full title: Australian experience with Ileocolic resections for Crohn’s disease. 5-year surgical and endoscopic recurrence rates and a review of the current anastomotic techniques and postoperative complications in the biologic era. 

Lead investigators: Dr Simon Ghaly and Dr Hugh Giddings  

Lead Site: St Vincent’s Hospital Sydney and Royal Prince Alfred Hospital  

Project overview and aims: As many as fifty percent of CD patients will require surgery within 10 years of diagnosis and 80% will require intestinal resection during their lifetime. Surgery is not curate and postoperative recurrence (POR) is inevitable with the relapsing nature of CD. There are some data suggesting that different surgical techniques (e.g. kono-S and degree of mesenteric excision) reduce Crohn’s disease recurrence rates after ileocolic resections.  There is a need to properly document what the current recurrence rates in Australia are during the biologic era to determine the need to change or advocate for a change in the type of anastomoses performed. This study aims to demonstrate the rates of surgical and endoscopic recurrence after ICR for CD in Australia and provide an accurate account of the anastomotic techniques being used and the current post-operative outcomes for this patient group.  

Data collection is occurring at 11 out of 17 of our ANZIBDC sites.